Nikhil Dholaria

Nikhil Dholaria

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The Role of Genetics in Neuroscience

The Role of Genetics in Neuroscience


Introduction The elusive nature of genetics has drawn much attention from a great number of neuroscientists and physicians. The genomic lock that contains the secrets behind thousands of disease states, pathophysiologies, and cellular mechanisms have been arduously studied ever since Mendel’s publication of "Experiments on Plant Hybri...

Epigenetic Mechanisms in the Pathology of Alzheimer's Disease

Epigenetic Mechanisms in the Pathology of Alzheimer's Disease


Abstract The presence of early-onset, familial Alzheimer’s disease (AD) is rare (around 3% to 5% of cases) and may be accredited to disease-causing mutations. More prevalent, by contrast, is the late-onset, sporadic (non-Mendelian) form of AD, which reflects the interaction of both genetic and environmental risk factors as well as the disr...