Sarah Shirley

Sarah Shirley

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Protein Dysregulation in Amyotrophic Lateral Sclerosis

Protein Dysregulation in Amyotrophic Lateral Sclerosis


Abstract Amyotrophic Lateral Sclerosis, also known as Lou Gehrig’s Disease, is a motor degenerative disease that causes loss of motor function. Several mechanisms, such as inflammation, prolonged excitation via excess glutamate, and disruption of mitochondrial function, have been proposed to contribute to the pathology of ALS.  Howeve...